Viral hemorrhagic fevers in the Tihamah region of the western Arabian Peninsula

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Viral hemorrhagic fevers in the Tihamah region of the western Arabian Peninsula

Viral hemorrhagic fever (VHF) refers to a group of diseases characterized by an acute febrile syndrome with hemorrhagic manifestations and high mortality rates caused by several families of viruses that affect humans and animals. These diseases are typically endemic in certain geographical regions and sometimes cause major outbreaks. The history of hemorrhagic fever in the Arabian Peninsula ref...

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Viral hemorrhagic fevers.

A taxonomically diverse set of single-stranded ribonucleic acid(ssRNA) viruses from four diverse viral families Arenaviridae,Bunyaviridae, Filoviridae, and Flaviviridae cause an acute systemic febrile syndrome called viral hemorrhagic fever (VHF). The syndrome produces combinations of prostration, malaise, increased vascular permeability, and coagulation maladies. In severe illness,VHF may incl...

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IMMUNOLOGY AND PATHOGENESIS OF VIRAL HEMORRHAGIC FEVERS Diagnostics and Discovery in Viral Hemorrhagic Fevers

The rate of discovery of new microbes and of new associations of microbes with health and disease is accelerating. Many factors contribute to this phenomenon including those that favor the true emergence of new pathogens as well as new technologies and paradigms that enable their detection and characterization. This chapter reviews recent progress in the field of pathogen surveillance and disco...

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The Role of Platelets in Viral Hemorrhagic Fevers

Arenaviridae, Bunyaviridae, Filoviridae and Flaviviridae are all RNA viruses that can induce a coagulopathy in infected patients. While there is a paucity of information on the cause of this coagulopathy, these viruses all produce a severe thrombocytopenia. Here, we review the literature on viral hemorrhagic fever and discuss the role played by platelets in the coagulopathy. We also discuss the...

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ژورنال

عنوان ژورنال: PLOS Neglected Tropical Diseases

سال: 2017

ISSN: 1935-2735

DOI: 10.1371/journal.pntd.0005322